OsmoTECH® XT Single-Sample Micro-Osmometer
Best-in-class osmolality performance
- Intelligent freezing technology reliably and accurately tests a wide variety of samples including complex matrices and highly viscous samples (i.e. sugars and proteins)
- Small sample volume uses only 20 μLs for testing
- Fully supports 21 CFR Part 11, GMP, and EU Annex 11 compliance
Best-in-class osmolality performance, designed with you in mind.
Advanced Instruments OsmoTECH XT empowers labs with accurate and precise osmolality analysis for a wide range of liquid samples across bioprocessing and cell & gene therapy workflows.
Streamline your osmolality workflow with a user-friendly interface and ensure robust data integrity with compliance features to match any digital environment.
Confidence in your process and quality control
Osmolality testing with OsmoTECH XT ensures reliable and robust analysis providing you with confidence in the development of a quality therapeutic. The OsmoTECH XT unlocks the next generation of freezing point depression testing to determine the osmolality of even the most complex samples. Engineered in collaboration with scientists across bioprocessing workflows to address the unique user and data security pain points found throughout every stage of the bioprocessing workflow.
Industry Applications
Biotech Labs
Maximize biologic yield, quality, and purity by optimizing and ensuring the quality and consistency of your buffers, media, product, excipients, and process parameters.
Food & Beverage Labs
Boost efficiency, ensure product quality, and maintain process consistency with osmolality testing from formulation to release.
Product Features
Intelligent freezing technology
- Only 20 μL sample volume with optimized cooling engine
- Measure even the most complex samples with more accuracy and precision
Experience widest range of osmolality 0 - 4000 mOsm/kgH2O
- Measure high concentrated solutions such as proteins and sugars
- Remove dilutions
Supports compliance
- 21 CFR part 11 / EU Annex 11
- e-Signature
- Three level user access
- Password protection
- And more
- GMP environment
- Pharmacopeia osmolality testing guidelines
Robust and flexible data management
- Network share (pdf & csv)
- Open Protocol Communication (OPC-UA)
- LIS (TCP/IP) Communication
- Bi-directional data management capability with OPC-UA to connect lab management (LIMS) and middleware software
- Active directory
- USB download
- Optional dot-matrix printer
One-step direct sampling
- Positive displacement sampler
- Aspirate highly viscous sample types (hyaluronate, cryopreservatives, etc.)
Preserve your audit trail
- Integrated barcode scanner for sample identification and reduced transcription errors
- Automatic, manual, synchronous back up
- Complete time-stamped record of usage, role, and actions requiring reason for settings changes
- Ability to annotate test results via the handy comments field
Simple user interface
- Large touchscreen
Optimized lab space
- Integrated consumable shelf
- Clean-room friendly consumables
MilkoScan™ FT3
The MilkoScan™ FT3 offers a new, intelligent approach to dairy analysis including the power to test a wide variety of liquid and semi-solid dairy products with exceptional uptime and unprecedented consistency of results.
Where can you analyse
In the laboratory or at-line
What can you analyse
Compositional analysis of liquid and semi-solid dairy products such as milk, cream, whey, yoghurt, creme fraiche, protein concentrates including WPC, chocolate milk and more.
Parameters
Global calibrations: Fat, protein, lactose incl. low lactose products, total solids, solids non fat, freezing point, titratable acidity, density, free fatty acids, citric acids, casein, urea, sucrose, glucose, fructose, galactose and fatty acid profiling. Targeted and untargeted adulteration screening.
Analysis time
30 seconds
Principle
FTIR
ProcesScan™ 2
ProcesScan™ 2 is a fully automated, on-line FTIR solution for standardization of milk and liquid dairy products with superior accuracy and speed. ProcesScan 2 offers a best-in-class solution for continuous and simultaneous analysis of milk composition parameters. Learn how to hit your targets continuously, ensure predictable performance and secure uptime.
Where can you analyse
In the production line: Close to the mixer, the blending unit or off the separator standardization.
What can you analyse
Milk and liquid dairy products
Parameters
Protein, fat, total solids, solids-non-fat (SNF), and lactose.
Analysis time
Continuous analysis with results every 10 seconds
Principle
FTIR
ProFoss™ 2 Milk Standardization
ProFoss™ 2 provides direct and continuous measurements, helping you to make the best use of raw materials in your fresh cheese/strained yoghurt production. Control variations of total solids and protein content in the process to produce closer to target specifications and confidently improve yield and profit while always meeting quality and legislative requirements.
Where can you analyse
In-line, in the pipe
What can you analyse
Fresh cheese/strained yoghurt
Parameters
Protein, total solids, moisture, fat
Analysis time
Real-time measurement
Principle
NIR
ProFoss™ 2 Fresh Cheese/Strained Yoghurt
ProFoss™ 2 provides direct and continuous measurements, helping you to make the best use of raw materials in your fresh cheese/strained yoghurt production. Control variations of total solids and protein content in the process to produce closer to target specifications and confidently improve yield and profit while always meeting quality and legislative requirements.
Where can you analyse
In the production process (in-line)
What can you analyse
Fresh cheese/strained yoghurt
Parameters
Protein, total solids, moisture, fat
Analysis time
Real-time measurement
Principle
NIR
BacSomatic™
The BacSomatic™ provides rapid hygiene testing of raw milk. It is the first-ever integrated bacteria and somatic cell tester and offers full-automation for minimal reagent handling and consistent test results. BacSomatic™ is ideal for dairies and smaller laboratories needing only a low-volume, yet high-performance analyser.
Where can you analyse
In a laboratory, control room at dairy or on-farm
What can you analyse
Raw cow's milk, buffalo milk and goat milk
Parameters
Bacteria count and somatic cell count
Analysis time
9.5 minutes (1.5 minutes for somatic cell alone)
Principle
Flow cytometry
CombiFoss™ 7
CombiFoss 7 seamlessly integrates MilkoScan™ 7 RM and Fossomatic™ 7 or Fossomatic™ 7 DC to test raw milk for up to 19 parameters including the new differential somatic cell count. FDA/NCIMS and MicroVal (EURL) approved. Cecalait approvals pending.
Where can you analyse
In the laboratory
What can you analyse
Raw milk (cow, goat, sheep, buffalo)
Parameters
Fat, protein (true and crude), casein, lactose, solids (SnF and TS), urea, citric acid, fatty acid profiling, FFA, freezing point depression, PH, ketosis screening (BHB and acetone), untargeted raw milk screening (adulteration), total somatic cell count (SCC) and differential somatic cell count (DSCC)
Analysis time
6-36 seconds depending on capacity level
Principle
FTIR and flow cytometry
FoodScan™ 2 Dairy
FoodScan™ 2 provides the analytical data you need about composition and colour. Improve the quality and consistency of solid and semi-solid dairy products and similar plant-based products while optimising production processes.
Where can you analyse
In the lab or at-line in harsh production environments
What can you analyse
Cheese, butter, spreads, fermented and cul-tured products such as yoghurt and skyr and similar plant-based products
Parameters
Fat, protein, moisture, salt, solids-non-fat, total solids and saturated fatty acids
Analysis time
As fast as 15 seconds
Principle
NIR
NIRS™ DS3 Dairy Analyser
Exceptional accuracy for analysis of milk powder, dairy powder and ice-cream mix. Know the quality of incoming raw materials and reduce your process variation.
Where can you analyse
In the lab or at-line in harsh production environments
What can you analyse
Dairy powders and ice-cream mix
Parameters
Fat, protein, moisture, ash, lactose, acidity and more
Analysis time
1 minute
Principle
NIR
ProFoss™ 2 Butter
ProFoss™ 2 Butter is an in-line analyser for accurate real time measurement of a range of dairy applications, monitoring the dairy production.
Where can you analyse
In-line, in the pipe
What can you analyse
Butter, fresh cheese, Greek yogurt, mozzarella, WPC/MPC, cream and dairy powders
Parameters
Fat, protein, moisture, total solids, solids non fat and protein-total solids ratio
Analysis time
Real time, continuous measurement – 2 - 3 seconds
Principle
NIR technology, Lateral transmittance
MilkoScan™ Mars
MilkoScan™ Mars is a highly cost effective milk tester, allowing you to measure up to six key parameters from a single milk sample.
Where can you analyse
In the lab
What can you analyse
Raw & processed milk, cream and whey
Parameters
Fat, protein, lactose, total solids, solids non-fat, freezing point (milk only).
Targeted and untargeted adulteration screening
Analysis time
1 minute
Principle
FTIR
ProFoss™ 2 Dairy
ProFoss™ 2 Dairy is an in-line dairy analyser for monitoring the dairy production.
Where can you analyse
In-line, in the pipe
What can you analyse
Butter, fresh cheese, Greek yogurt, mozzarella, WPC/MPC, cream and dairy powders
Parameters
Fat, protein, moisture, total solids, solids non fat and protein-total solids ratio
Analysis time
Real time, continuous measurement – 1,5-3 seconds
Principle
NIR technology, Lateral transmittance
BactoScan™ FC+
Based on the measurement of Individual Bacteria Count (IBC), BactoScan™ FC+ gives an accurate determination of the hygienic quality of raw milk with a capacity of testing up to 200 samples per hour. FDA/NCIMS and MicroVal (EURL) accepted method.
Where can you analyse
In the laboratory
What can you analyse
Raw milk (cow, goat, sheep, buffalo)
Parameters
Individual Bacteria Count (IBC)
Analysis time
9 min
Principle
Flow cytometry
DairyScan™
Cheese analyser for fast and accurate fat and moisture testing.
Where can you analyse
In the lab
What can you analyse
Cheese
Parameters
Fat and moisture
Analysis time
45 sec.
Principle
NIR
Kjeltec™ 9 Analyser - Automated Kjeldahl Analysis
Fully automated Kjeldahl analyser adding advanced digital capabilities to an already brilliant technology. Fast turnaround time, improved data handling and less risk of human error for accurate results.
Where can you analyse
In the laboratory
What can you analyse
Nitrogen, protein, ammonia
Parameters
Raw materials and finished products in food, feed and agriculture
Analysis time
3.5 minutes at 30 mg N (6.5 minutes at 200 mg N)
Principle
Technology - Kjeldahl and other nitrogen based chemical analysis
Kjeltec™ 9 Distillator
Automated distillation unit for protein analysis and other distillation purposes following the Kjeldahl method. The solution is perfect for laboratories running a low to medium volume of daily samples and using many different distillation methods.
Where can you analyse
In the laboratory
What can you analyse
Nitrogen, protein and ammonia
Parameters
Raw materials and finished products in food, feed and agriculture
Analysis time
3.5 minutes at 30 mg N (6.5 minutes at 200 mg N)
Principle
Technology - Kjeldahl and other nitrogen based chemical analysis
Kjeltec™ 8100
Semi-automated distillation unit following the official Kjeldahl method
Where can you analyse
In the laboratory
What can you analyse
Food, feed, feed ingredients, forage, pet food, grain, cereal, oil seeds meat, meat products, milk, dairy products, beer and beer ingredients
Parameters
Nitrogen, protein, Non Protein Nitrogen (NPN) and volatiles (SO2, TVBN and more)
Analysis time
3-5 minutes
Principle
Kjeldahl distillation
Autosampler for Kjeltec™ 9 Analyser
In combination with a Kjeltec™ 9 Analyser, FOSS Autosamplers provide fully automated Kjeldahl analysis. Choose between the 20 or 60 place AutoSampler to increase your sample throughput and free up staff to do other work.
Where can you analyse
In the laboratory
What can you analyse
Nitrogen, protein, ammonia
Parameters
Raw materials and finished products in food, feed and agriculture
Analysis time
3.5 minutes at 30 mg N (6.5 minutes at 200 mg N)
Principle
Technology - Batch handling
Soxtec™ 8000
First fully automated Soxhlet for fast and safe crude and total fat analysis
Where can you analyse
In the laboratory
What can you analyse
Feed, feed ingredients, forage, pet food, food, food ingredients, grain, cereal, oil seeds, DDGS, meat, meat products, fish, fish products, dairy products, environmental products, and other industry products
Parameters
Crude fat, total fat and extractable matter
Analysis time
45-60 minutes
Principle
Randall improved Soxhlet
Fibertec™ 8000
Fully automated fibre analysis system
Where can you analyse
In the laboratory
What can you analyse
Feed, feed ingredients, forage, pet food, grain, cereal and oil seeds
Parameters
Crude Fibre (CF), Neutral Detergent Fibre (NDF), Acid Detergent Fibre (ADF) and Acid Detergent Lignin (ADL)
Analysis time
Total analysis time 2 hours, operator time 2 minutes
Principle
Fibre determination according to standard methods
4250 Single-Sample Cryoscope
The high-performance reference method for determining the freezing point of milk.
- Trusted results in just 90 seconds!
- Low maintenance - proven robustness & reliability
- Supports compliance with regulatory standards
Assured Monitoring of Milk Supply Process and Product Integrity
The Model 4250 Single-Sample Cryoscope allows your plant to manage a premium milk supply, ensure quality products and improve your operating efficiency. The system is the fastest, most reliable, and precise system for milk analysis and it utilizes the industry preferred freezing point depression (FPD) method for determination of added water to milk.
Designed for reliable monitoring of added water in milk
The Model 4250 Cryoscope is designed to sense sample temperature by using high precision thermistors. It then controls the degree of super-cooling and freeze induction, and measures the freezing point of the sample in just two minutes.
For Dairy Labs
- Determination of added water in raw cow*, sheep, goat, buffalo and camel milks.
- Checkpoint indicator for sour or contaminated raw milk.
- Can indicate the presence of water in milking machine pipes, undrained bulk tanks, and other types of water dilution at the milk producer’s site.*Able to determine added water in pasteurized, UHT-treated, and sterilized whole or partially skimmed cow milk.
Product Features
Versatile
- International Reference Method of Plateau Seeking (ISO/FDIS-5764/IDF 108)
- Standard timed plateau methods
- Millidegrees Celsius (m°C) and millidegrees Horvett (m°H)
Robust
- Low maintenance; the sample probe and stir-wire are fully accessible for easy cleaning
Data handling
- Optional barcode scanner for supplier ID numbers
- On-board printer for better traceability, tracking
- meet HACCP requirements
- RS-232 communication capability for data transfer
Customize user experience
- Multiple language display settings
Ease of use
- Rapid and stable automated calibration procedure
- Two minute test time
- High throughput of samples
Cryoline standards
- Advanced Instruments calibrators, controls and supplies meet the exacting standard required to fulfill ISO, HACCP and QA/QC laboratories
OsmoTECH® XT Single-Sample Micro-Osmometer
Best-in-class osmolality performance
- Intelligent freezing technology reliably and accurately tests a wide variety of samples including complex matrices and highly viscous samples (i.e. sugars and proteins)
- Small sample volume uses only 20 μLs for testing
- Fully supports 21 CFR Part 11, GMP, and EU Annex 11 compliance
Best-in-class osmolality performance, designed with you in mind.
Advanced Instruments OsmoTECH XT empowers labs with accurate and precise osmolality analysis for a wide range of liquid samples across bioprocessing and cell & gene therapy workflows.
Streamline your osmolality workflow with a user-friendly interface and ensure robust data integrity with compliance features to match any digital environment.
Confidence in your process and quality control
Osmolality testing with OsmoTECH XT ensures reliable and robust analysis providing you with confidence in the development of a quality therapeutic. The OsmoTECH XT unlocks the next generation of freezing point depression testing to determine the osmolality of even the most complex samples. Engineered in collaboration with scientists across bioprocessing workflows to address the unique user and data security pain points found throughout every stage of the bioprocessing workflow.
Industry Applications
Biotech Labs
Maximize biologic yield, quality, and purity by optimizing and ensuring the quality and consistency of your buffers, media, product, excipients, and process parameters.
Food & Beverage Labs
Boost efficiency, ensure product quality, and maintain process consistency with osmolality testing from formulation to release.
Product Features
Intelligent freezing technology
- Only 20 μL sample volume with optimized cooling engine
- Measure even the most complex samples with more accuracy and precision
Experience widest range of osmolality 0 - 4000 mOsm/kgH2O
- Measure high concentrated solutions such as proteins and sugars
- Remove dilutions
Supports compliance
- 21 CFR part 11 / EU Annex 11
- e-Signature
- Three level user access
- Password protection
- And more
- GMP environment
- Pharmacopeia osmolality testing guidelines
Robust and flexible data management
- Network share (pdf & csv)
- Open Protocol Communication (OPC-UA)
- LIS (TCP/IP) Communication
- Bi-directional data management capability with OPC-UA to connect lab management (LIMS) and middleware software
- Active directory
- USB download
- Optional dot-matrix printer
One-step direct sampling
- Positive displacement sampler
- Aspirate highly viscous sample types (hyaluronate, cryopreservatives, etc.)
Preserve your audit trail
- Integrated barcode scanner for sample identification and reduced transcription errors
- Automatic, manual, synchronous back up
- Complete time-stamped record of usage, role, and actions requiring reason for settings changes
- Ability to annotate test results via the handy comments field
Simple user interface
- Large touchscreen
Optimized lab space
- Integrated consumable shelf
- Clean-room friendly consumables
Milk centrifuge Gerber Micro III
With our small centrifuge Micro III these methods can be carried out:
- Fat determination according to Gerber or
- Fat determination according to Babcock
The Gerber centrifuge Micro III with high safety standards and reliability and these product features:
- Strong sheet steel housing with an acid-resistent paint work
- Cover lock to prevent opening of the centrifuge during operation
- Motor with elastic bearing for smooth run
- New – Increased precision thanks to controlled speed
- New – Unbalance shut-off through uneven filling or sudden glass break
Milk centrifuge Gerber Compact III
With our new multipurpose centrifuge Compact III these methods can be carried out:
- Fat determination according to Gerber and Babcock
- Solubility determination according to Gerber and ADPI
The Gerber centrifuge Compact III with high safety standards and reliability and these product features:
- Strong sheet steel housing with an acid-resistent paint work
- Cover lock to prevent opening of the centrifuge during Operation
- Unbalance shut-off through uneven filling or sudden glass break
- Motor with elastic bearing for smooth run
- Increased precision thanks to controlled speed
novaLUM II-X System
Industries
- Dairy
- Feed and Grain
- On the Farm
- Food & Beverage
- Water
- Healthcare
The novaLUM II-X system brings together Charm’s trusted ATP (adenosine triphosphate) detection technology and sophisticated new novaLINK 5 software to create a powerful system that makes sanitation verification, corrective action, and documentation easier than ever.
With the novaLUM II-X system you can optimize your real-time sanitation monitoring and can easily utilize collect data to evaluate and improve your sanitation program. With an effective sanitation program, you will be able to reduce microbial challenges, improve product quality, reduce customer complaints, extend product shelf life, and protect your brand from product recalls.
In conjunction with Charm’s PocketSwab Plus, FieldSwab, WaterGiene, and AllerGiene tests, the novaLUM II-X system is used for sanitation and allergen control, pasteurization verification, and pesticide screening. In just five seconds, the novaLUM II-X system is able to detect even the lowest levels of ATP contamination.
The novaLUM II-X system syncs data from the instrument to local or corporate databases and can identify and report failing swab sites during sanitation for immediate management review. The novaLINK 5 software identifies locations that repeatedly fail and creates randomized sampling plans based on risk assessment. Targeting areas with sanitation deficiencies helps to control sanitation costs and investigate SSOP. Automated reporting streamlines corrective action through the novaLUM II-X system, providing documentation to meet the requirements of third-party audits, i.e. SQF, BRC, and FSSC.
Benefits
- Detects ATP in 5 seconds
- Syncs and reports results in real-time via WiFi
- Utilizes data to create SMART Plans
- Provides documentation for third party audits
Charm II System
Industries
- Dairy
- Feed and Grain
- Food & Beverage
The Charm II system provides comprehensive food safety testing for multiple food matrices. The Charm II system is used to test for a wide range of residues in milk, egg, fish, grain, honey, serum, tissue, urine, and water testing.
With the Charm II system, laboratories can test for the following residues:
- Antibiotics, including aminoglycosides, amphenicols, beta-lactams, macrolides, novobiocin, sulfonamides, and tetracyclines
- Aflatoxin B1 in grain and aflatoxin M1 in milk
- Pesticides, using the Charm CideLite test
- Alkaline phosphatase (a biomarker for incomplete pasteurization), using the Charm PasLite test
- ATP (for hygiene), using the PocketSwab Plus and other Charm swabs.
The Charm II system is the choice of food industry laboratories and regulators around the world because of the wide variety of tests offered and the system’s versatility, reliability, and accuracy.
Many labs use the Charm II system to screen food products for domestic monitoring or international trade. Other labs use the Charm II in conjunction with HPLC to detect and identify specific antimicrobial drugs and their metabolites.
Benefits
- Tests multiple food matrices for a wide variety of residues
- Detection capabilities to US Safe Levels and to EU and CODEX MRLs; many tests are approved by FDA and the US National Conference of Interstate Milk - Shippers (NCIMS)
- Streamlined extraction and assay methods
- Most assays take only 10 to 15 minutes
- Optional C2soft data acquisition and management software
Regulatory Info
- Approved by US National Conference on Interstate Milk Shipments (NCIMS)
- FDA approval M-I-13-2
- Approved by the State Committee for Standardization of the Republic of Belarus (Gosstandart)
EPIC
Industries
- Dairy
- Food & Beverage
The Charm EPIC system is a microplate bioluminescence system that predicts spoilage in shelf-stable, ultra high temperature (UHT), and extended shelf life (ESL) beverage products.
EPIC detects ATP, a bio-marker of microbiological quality. The EPIC system can screen beverage products in as little as 24 to 36 hours.
The product is incubated in its original package (PET bottle, carton, single serve) to accelerate the microbial growth of any bacteria present. After incubation, samples are pipetted into a microplate and inserted in the EPIC system. EPIC automatically performs reagent additions, incubations, readings, and analysis. Data is managed by EPICLink software, which provides real-time analysis, trending, and editing capabilities.
Products that can be tested include white milks, flavored milks, soy beverages, creams, yogurt-based drinks, lactose-free milk, ice cream and shake mixes, rice milk, condensed milk, broths, and nutritional drinks.
Benefits
- Fast results reduce warehouse hold times
- Only 24 to 36 hours incubation needed for most products
- Thirty minutes testing time for a full 96-well plate
- Patented microplate mask eliminates interference between wells
- Reagents are sized so that all can be changed at the same time without waste
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